Preeclampsia and sperm exposure

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A study of how two immune system-related factors — one genetic and one sexual — combine to affect risk could yield strategies for planning pregnancies with improved awareness and management of the odds for being affected by that complication. A report of new research, now in press at the Journal of Reproductive Immunology, documents how two distinct risk factors combine to affect the odds that a first-time mother could develop the sometimes life-threatening pregnancy complication. The findings suggest there could be new ways to plan pregnancy with improved awareness and management of the risk. For that reason, researchers have been studying the potential role of two risk factors: The new study, first published online in August, measured both of those risk factors in detail and in combination in women who developed preeclampsia and in similar women who did not. The analysis accounted for other risk factors, such as Body Mass Index.
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Open in a separate window a Data are given as mean SD or numbers percent. Adjusted for age, BMI, aspirin or calcium use, passive smoking, level of education and planned pregnancy. In 2 months before pregnancy. Student t-test and the Mann—Whitney U-test were applied to quantitative variables. The x2 and Fisher's methods were applied to qualitative variables. Discussion Results demonstrated that a short duration of sperm exposure and short duration of cohabitation increased the risk of preeclampsia.
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Correlation between oral sex and a low incidence of preeclampsia: The involvement of immune mechanisms in the aetiology of preeclampsia is often suggested. Normal pregnancy is thought to be associated with a state of tolerance to the foreign antigens of the fetus, whereas in preeclamptic women this immunological tolerance might be hampered. The present study shows that oral sex and swallowing sperm is correlated with a diminished occurrence of preeclampsia which fits in the existing idea that a paternal factor is involved in the occurrence of preeclampsia.
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By Honor Whiteman Researchers have discovered how one genetic and one sexual risk factor can combine to increase the risk of preeclampsia, according to a study published in the Journal of Reproductive Immunology. Elizabeth Triche and colleagues at Brown University say their findings suggest there could be new ways for couples to plan pregnancy with improved awareness of the disorder, as well as improved management of the risks. Preeclampsia is a common condition that can occur during pregnancy, most typically during the postpartum period.
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